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The Encapsulation of Hemagglutinin in Protein Bodies Achieves a Stronger Immune Response in Mice than the Soluble Antigen

Zein is a water-insoluble polymer from maize seeds that has been widely used to produce carrier particles for the delivery of therapeutic molecules. We encapsulated a recombinant model vaccine antigen in newly formed zein bodies in planta by generating a fusion construct comprising the ectodomain of...

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Detalles Bibliográficos
Autores principales: Hofbauer, Anna, Melnik, Stanislav, Tschofen, Marc, Arcalis, Elsa, Phan, Hoang T., Gresch, Ulrike, Lampel, Johannes, Conrad, Udo, Stoger, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754457/
https://www.ncbi.nlm.nih.gov/pubmed/26909090
http://dx.doi.org/10.3389/fpls.2016.00142