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The Encapsulation of Hemagglutinin in Protein Bodies Achieves a Stronger Immune Response in Mice than the Soluble Antigen
Zein is a water-insoluble polymer from maize seeds that has been widely used to produce carrier particles for the delivery of therapeutic molecules. We encapsulated a recombinant model vaccine antigen in newly formed zein bodies in planta by generating a fusion construct comprising the ectodomain of...
Autores principales: | Hofbauer, Anna, Melnik, Stanislav, Tschofen, Marc, Arcalis, Elsa, Phan, Hoang T., Gresch, Ulrike, Lampel, Johannes, Conrad, Udo, Stoger, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754457/ https://www.ncbi.nlm.nih.gov/pubmed/26909090 http://dx.doi.org/10.3389/fpls.2016.00142 |
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