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Isosteviol Sensitizes sarcK(ATP) Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes

K(ATP) channel is an important mediator or factor in physiological and pathological metabolic pathway. Activation of K(ATP) channel has been identified to be a critical step in the cardioprotective mechanism against IR injury. On the other hand, desensitization of the channel to its opener or the me...

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Detalles Bibliográficos
Autores principales: Fan, Zhuo, Wen, Ting, Chen, Yaoxu, Huang, Lijie, Lin, Wei, Yin, Chunxia, Tan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754489/
https://www.ncbi.nlm.nih.gov/pubmed/26949448
http://dx.doi.org/10.1155/2016/6362812