Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses

Due to their ability to knock down the expression of any gene, siRNAs have been heralded as ideal candidates for treating a wide variety of diseases, including those involving “undruggable” targets. However, the therapeutic potential of siRNAs remains severely limited by a lack of effective delivery...

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Detalles Bibliográficos
Autores principales: Katakowski, Joseph A, Mukherjee, Gayatri, Wilner, Samantha E, Maier, Keith E, Harrison, Michael Travis, DiLorenzo, Teresa P, Levy, Matthew, Palliser, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754549/
https://www.ncbi.nlm.nih.gov/pubmed/26412590
http://dx.doi.org/10.1038/mt.2015.175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754549/
https://www.ncbi.nlm.nih.gov/pubmed/26412590
http://dx.doi.org/10.1038/mt.2015.175

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