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Delivery of siRNAs to Dendritic Cells Using DEC205-Targeted Lipid Nanoparticles to Inhibit Immune Responses
Due to their ability to knock down the expression of any gene, siRNAs have been heralded as ideal candidates for treating a wide variety of diseases, including those involving “undruggable” targets. However, the therapeutic potential of siRNAs remains severely limited by a lack of effective delivery...
Autores principales: | Katakowski, Joseph A, Mukherjee, Gayatri, Wilner, Samantha E, Maier, Keith E, Harrison, Michael Travis, DiLorenzo, Teresa P, Levy, Matthew, Palliser, Deborah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754549/ https://www.ncbi.nlm.nih.gov/pubmed/26412590 http://dx.doi.org/10.1038/mt.2015.175 |
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