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Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
Motivation: High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estimates of read-count variability. These estimates are typically based on statistical models such as the negati...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754627/ https://www.ncbi.nlm.nih.gov/pubmed/26206307 http://dx.doi.org/10.1093/bioinformatics/btv425 |