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Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment

Motivation: High-throughput RNA sequencing (RNA-seq) is now the standard method to determine differential gene expression. Identifying differentially expressed genes crucially depends on estimates of read-count variability. These estimates are typically based on statistical models such as the negati...

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Detalles Bibliográficos
Autores principales: Gierliński, Marek, Cole, Christian, Schofield, Pietà, Schurch, Nicholas J., Sherstnev, Alexander, Singh, Vijender, Wrobel, Nicola, Gharbi, Karim, Simpson, Gordon, Owen-Hughes, Tom, Blaxter, Mark, Barton, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754627/
https://www.ncbi.nlm.nih.gov/pubmed/26206307
http://dx.doi.org/10.1093/bioinformatics/btv425