Treatment of beta amyloid 1–42 (Aβ(1–42))-induced basal forebrain cholinergic damage by a non-classical estrogen signaling activator in vivo

In Alzheimer’s disease (AD), there is a loss in cholinergic innervation targets of basal forebrain which has been implicated in substantial cognitive decline. Amyloid beta peptide (Aβ(1–42)) accumulates in AD that is highly toxic for basal forebrain cholinergic (BFC) neurons. Although the gonadal st...

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Detalles Bibliográficos
Autores principales: Kwakowsky, Andrea, Potapov, Kyoko, Kim, SooHyun, Peppercorn, Katie, Tate, Warren P., Ábrahám, István M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754683/
https://www.ncbi.nlm.nih.gov/pubmed/26879842
http://dx.doi.org/10.1038/srep21101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754683/
https://www.ncbi.nlm.nih.gov/pubmed/26879842
http://dx.doi.org/10.1038/srep21101

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