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MRN, CtIP, and BRCA1 mediate repair of topoisomerase II–DNA adducts
Repair of DNA double-strand breaks (DSBs) with complex ends poses a special challenge, as additional processing is required before DNA ligation. For example, protein–DNA adducts must be removed to allow repair by either nonhomologous end joining or homology-directed repair. Here, we investigated the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754713/ https://www.ncbi.nlm.nih.gov/pubmed/26880199 http://dx.doi.org/10.1083/jcb.201504005 |