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Biophysical changes reduce energetic demand in growth factor–deprived lymphocytes

Cytokine regulation of lymphocyte growth and proliferation is essential for matching nutrient consumption with cell state. Here, we examine how cellular biophysical changes that occur immediately after growth factor depletion promote adaptation to reduced nutrient uptake. After growth factor withdra...

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Detalles Bibliográficos
Autores principales: Hecht, Vivian C., Sullivan, Lucas B., Kimmerling, Robert J., Kim, Dong-Hwee, Hosios, Aaron M., Stockslager, Max A., Stevens, Mark M., Kang, Joon Ho, Wirtz, Denis, Vander Heiden, Matthew G., Manalis, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754715/
https://www.ncbi.nlm.nih.gov/pubmed/26880201
http://dx.doi.org/10.1083/jcb.201506118