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Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway
Primary cilia protrude from the surface of quiescent cells and disassemble at cell cycle reentry. We previously showed that ciliary reassembly is suppressed by trichoplein-mediated Aurora A activation pathway in growing cells. Here, we report that Ndel1, a well-known modulator of dynein activity, lo...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754717/ https://www.ncbi.nlm.nih.gov/pubmed/26880200 http://dx.doi.org/10.1083/jcb.201507046 |