Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein–Aurora A pathway

Primary cilia protrude from the surface of quiescent cells and disassemble at cell cycle reentry. We previously showed that ciliary reassembly is suppressed by trichoplein-mediated Aurora A activation pathway in growing cells. Here, we report that Ndel1, a well-known modulator of dynein activity, lo...

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Detalles Bibliográficos
Autores principales: Inaba, Hironori, Goto, Hidemasa, Kasahara, Kousuke, Kumamoto, Kanako, Yonemura, Shigenobu, Inoko, Akihito, Yamano, Shotaro, Wanibuchi, Hideki, He, Dongwei, Goshima, Naoki, Kiyono, Tohru, Hirotsune, Shinji, Inagaki, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754717/
https://www.ncbi.nlm.nih.gov/pubmed/26880200
http://dx.doi.org/10.1083/jcb.201507046

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