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Coupling primary and stem cell–derived cardiomyocytes in an in vitro model of cardiac cell therapy

The efficacy of cardiac cell therapy depends on the integration of existing and newly formed cardiomyocytes. Here, we developed a minimal in vitro model of this interface by engineering two cell microtissues (μtissues) containing mouse cardiomyocytes, representing spared myocardium after injury, and...

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Detalles Bibliográficos
Autores principales: Aratyn-Schaus, Yvonne, Pasqualini, Francesco S., Yuan, Hongyan, McCain, Megan L., Ye, George J.C., Sheehy, Sean P., Campbell, Patrick H., Parker, Kevin Kit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754718/
https://www.ncbi.nlm.nih.gov/pubmed/26858266
http://dx.doi.org/10.1083/jcb.201508026