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Altered drug susceptibility during host adaptation of a Plasmodium falciparum strain in a non-human primate model

Infections with Plasmodium falciparum, the most pathogenic of the Plasmodium species affecting man, have been reduced in part due to artemisinin-based combination therapies. However, artemisinin resistant parasites have recently emerged in South-East Asia. Novel intervention strategies are therefore...

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Detalles Bibliográficos
Autores principales: Obaldía III, Nicanor, Dow, Geoffrey S., Gerena, Lucia, Kyle, Dennis, Otero, William, Mantel, Pierre-Yves, Baro, Nicholas, Daniels, Rachel, Mukherjee, Angana, Childs, Lauren M., Buckee, Caroline, Duraisingh, Manoj T., Volkman, Sarah K., Wirth, Dyann F., Marti, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754742/
https://www.ncbi.nlm.nih.gov/pubmed/26880111
http://dx.doi.org/10.1038/srep21216