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Mechanical stretching stimulates collagen synthesis via down-regulating SO(2)/AAT1 pathway

The aim of the study was to investigate the role of endogenous sulfur dioxide (SO(2))/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO(2)/AAT1 pathway and increased collagen I and III protein expr...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Yu, Wen, Liu, Yan, Chen, Selena, Huang, Yaqian, Li, Xiaohui, Liu, Cuiping, Zhang, Yanqiu, Li, Zhenzhen, Du, Jie, Tang, Chaoshu, Du, Junbao, Jin, Hongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754767/
https://www.ncbi.nlm.nih.gov/pubmed/26880260
http://dx.doi.org/10.1038/srep21112