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Mechanical stretching stimulates collagen synthesis via down-regulating SO(2)/AAT1 pathway
The aim of the study was to investigate the role of endogenous sulfur dioxide (SO(2))/ aspartate aminotransferase 1 (AAT1) pathway in stretch-induced excessive collagen expression and its mechanism. The mechanical stretch downregulated SO(2)/AAT1 pathway and increased collagen I and III protein expr...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754767/ https://www.ncbi.nlm.nih.gov/pubmed/26880260 http://dx.doi.org/10.1038/srep21112 |