Identification of different mechanisms leading to PAX6 down-regulation as potential events contributing to the onset of Hirschsprung disease

Hirschsprung disease (HSCR) is attributed to a failure of neural crest derived cells to migrate, proliferate, differentiate or survive in the bowel wall during embryonic Enteric Nervous System (ENS) development. This process requires a wide and complex variety of molecules and signaling pathways whi...

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Detalles Bibliográficos
Autores principales: Enguix-Riego, María Valle, Torroglosa, Ana, Fernández, Raquel María, Moya-Jiménez, María José, de Agustín, Juan Carlos, Antiñolo, Guillermo, Borrego, Salud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754768/
https://www.ncbi.nlm.nih.gov/pubmed/26879676
http://dx.doi.org/10.1038/srep21160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754768/
https://www.ncbi.nlm.nih.gov/pubmed/26879676
http://dx.doi.org/10.1038/srep21160

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