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Three-dimensional Organotypic Culture Models of Human Hepatocellular Carcinoma

Three-dimensional cell culture methods are viable in vitro approaches that facilitate the examination of biological features cancer cells present in vivo. In this study, we demonstrate that hepatocellular carcinoma (HCC) cells in porous alginate scaffolds can generate organoid-like spheroids that mi...

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Detalles Bibliográficos
Autores principales: Takai, Atsushi, Fako, Valerie, Dang, Hien, Forgues, Marshonna, Yu, Zhipeng, Budhu, Anuradha, Wang, Xin Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754778/
https://www.ncbi.nlm.nih.gov/pubmed/26880118
http://dx.doi.org/10.1038/srep21174