Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma

BACKGROUND: A current focus in cancer treatment is to broaden responses to immunotherapy. One reason these therapies may prove inadequate is that T lymphocytes fail to recognize the tumor due to differences in immunogenic epitopes presented by the cancer cells under inflammatory or non-inflammatory...

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Detalles Bibliográficos
Autores principales: Woods, Katherine, Knights, Ashley J., Anaka, Matthew, Schittenhelm, Ralf B., Purcell, Anthony W., Behren, Andreas, Cebon, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754849/
https://www.ncbi.nlm.nih.gov/pubmed/26885372
http://dx.doi.org/10.1186/s40425-016-0111-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754849/
https://www.ncbi.nlm.nih.gov/pubmed/26885372
http://dx.doi.org/10.1186/s40425-016-0111-7

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