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Mismatch in epitope specificities between IFNγ inflamed and uninflamed conditions leads to escape from T lymphocyte killing in melanoma
BACKGROUND: A current focus in cancer treatment is to broaden responses to immunotherapy. One reason these therapies may prove inadequate is that T lymphocytes fail to recognize the tumor due to differences in immunogenic epitopes presented by the cancer cells under inflammatory or non-inflammatory...
Autores principales: | Woods, Katherine, Knights, Ashley J., Anaka, Matthew, Schittenhelm, Ralf B., Purcell, Anthony W., Behren, Andreas, Cebon, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754849/ https://www.ncbi.nlm.nih.gov/pubmed/26885372 http://dx.doi.org/10.1186/s40425-016-0111-7 |
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