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Statistical correlation of nonconservative substitutions of HIV gp41 variable amino acid residues with the R5X4 HIV-1 phenotype

BACKGROUND: The interaction of the envelope glycoprotein of HIV-1 (gp120/gp41) with coreceptor molecules has important implications for specific cellular targeting and pathogenesis. Experimental and theoretical evidences have shown a role for gp41 in coreceptor tropism, although there is no consensu...

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Detalles Bibliográficos
Autores principales:	Pacheco-Martínez, Elena, Figueroa-Medina, Evangelina, Villarreal, Carlos, Cocho, Germinal, Medina-Franco, José L., Méndez-Lucio, Oscar, Huerta, Leonor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754869/ https://www.ncbi.nlm.nih.gov/pubmed/26879054 http://dx.doi.org/10.1186/s12985-016-0486-6

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