Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes

BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders, iNOS is also involved in diabetic vascular d...

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Detalles Bibliográficos
Autores principales: Nassi, Alberto, Malorgio, Francesca, Tedesco, Serena, Cignarella, Andrea, Gaion, Rosa Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754884/
https://www.ncbi.nlm.nih.gov/pubmed/26879172
http://dx.doi.org/10.1186/s12933-016-0349-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754884/
https://www.ncbi.nlm.nih.gov/pubmed/26879172
http://dx.doi.org/10.1186/s12933-016-0349-x

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