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Upregulation of inducible NO synthase by exogenous adenosine in vascular smooth muscle cells activated by inflammatory stimuli in experimental diabetes
BACKGROUND: Adenosine has been shown to induce nitric oxide (NO) production via inducible NO synthase (iNOS) activation in vascular smooth muscle cells (VSMCs). Although this is interpreted as a beneficial vasodilating pathway in vaso-occlusive disorders, iNOS is also involved in diabetic vascular d...
Autores principales: | Nassi, Alberto, Malorgio, Francesca, Tedesco, Serena, Cignarella, Andrea, Gaion, Rosa Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754884/ https://www.ncbi.nlm.nih.gov/pubmed/26879172 http://dx.doi.org/10.1186/s12933-016-0349-x |
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