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Attenuation of teratoma formation by p27 overexpression in induced pluripotent stem cells

BACKGROUND: Pluripotent stem cells, such as embryonic stem cells or induced pluripotent stem cells, have a great potential for regenerative medicine. Induced pluripotent stem cells, in particular, are suitable for replacement of tissue by autologous transplantation. However, tumorigenicity is a majo...

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Detalles Bibliográficos
Autores principales: Matsu-ura, Toru, Sasaki, Hiroshi, Okada, Motoi, Mikoshiba, Katsuhiko, Ashraf, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754927/
https://www.ncbi.nlm.nih.gov/pubmed/26880084
http://dx.doi.org/10.1186/s13287-016-0286-3