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Attenuation of teratoma formation by p27 overexpression in induced pluripotent stem cells
BACKGROUND: Pluripotent stem cells, such as embryonic stem cells or induced pluripotent stem cells, have a great potential for regenerative medicine. Induced pluripotent stem cells, in particular, are suitable for replacement of tissue by autologous transplantation. However, tumorigenicity is a majo...
Autores principales: | Matsu-ura, Toru, Sasaki, Hiroshi, Okada, Motoi, Mikoshiba, Katsuhiko, Ashraf, Muhammad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754927/ https://www.ncbi.nlm.nih.gov/pubmed/26880084 http://dx.doi.org/10.1186/s13287-016-0286-3 |
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