Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

Identifying whether potential causal variants for related diseases are shared can identify overlapping etiologies of multifactorial disorders. Colocalization methods disentangle shared and distinct causal variants. However, existing approaches require independent datasets. Here we extend two colocal...

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Detalles Bibliográficos
Autores principales: Fortune, Mary D., Guo, Hui, Burren, Oliver, Schofield, Ellen, Walker, Neil M., Ban, Maria, Sawcer, Stephen J., Bowes, John, Worthington, Jane, Barton, Ann, Eyre, Steve, Todd, John A., Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754941/
https://www.ncbi.nlm.nih.gov/pubmed/26053495
http://dx.doi.org/10.1038/ng.3330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754941/
https://www.ncbi.nlm.nih.gov/pubmed/26053495
http://dx.doi.org/10.1038/ng.3330

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