LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development

The secreted leucine-rich glioma inactivated 1 (LGI1) protein is an important actor for human seizures of both genetic and autoimmune etiology: mutations in LGI1 cause inherited temporal lobe epilepsy, while LGI1 is involved in antibody-mediated encephalitis. Remarkably, Lgi1-deficient (Lgi1(−/−)) m...

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Detalles Bibliográficos
Autores principales: Boillot, Morgane, Lee, Chun-Yao, Allene, Camille, Leguern, Eric, Baulac, Stéphanie, Rouach, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754946/
https://www.ncbi.nlm.nih.gov/pubmed/26878798
http://dx.doi.org/10.1038/srep21769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754946/
https://www.ncbi.nlm.nih.gov/pubmed/26878798
http://dx.doi.org/10.1038/srep21769

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