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LGI1 acts presynaptically to regulate excitatory synaptic transmission during early postnatal development
The secreted leucine-rich glioma inactivated 1 (LGI1) protein is an important actor for human seizures of both genetic and autoimmune etiology: mutations in LGI1 cause inherited temporal lobe epilepsy, while LGI1 is involved in antibody-mediated encephalitis. Remarkably, Lgi1-deficient (Lgi1(−/−)) m...
Autores principales: | Boillot, Morgane, Lee, Chun-Yao, Allene, Camille, Leguern, Eric, Baulac, Stéphanie, Rouach, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754946/ https://www.ncbi.nlm.nih.gov/pubmed/26878798 http://dx.doi.org/10.1038/srep21769 |
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