Efficient conversion of primary azides to aldehydes catalyzed by active site variants of myoglobin

The oxidation of primary azides to aldehydes constitutes a convenient but underdeveloped transformation for which no efficient methods are available. Here, we demonstrate that engineered variants of the hemoprotein myoglobin can catalyze this transformation with high efficiency (up to 8500 turnovers...

Descripción completa

Detalles Bibliográficos
Autores principales: Giovani, Simone, Singh, Ritesh, Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754990/
https://www.ncbi.nlm.nih.gov/pubmed/26900445
http://dx.doi.org/10.1039/c5sc02857d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754990/
https://www.ncbi.nlm.nih.gov/pubmed/26900445
http://dx.doi.org/10.1039/c5sc02857d

Ejemplares similares