Death receptor-based enrichment of Cas9-expressing cells

BACKGROUND: The CRISPR/Cas9 genome editing system has greatly facilitated and expanded our capacity to engineer mammalian genomes, including targeted gene knock-outs. However, the phenotyping of the knock-out effect requires a high DNA editing efficiency. RESULTS: Here, we report a user-friendly str...

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Detalles Bibliográficos
Autores principales: Liesche, C., Venkatraman, L., Aschenbrenner, S., Grosse, S., Grimm, D., Eils, R., Beaudouin, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755021/
https://www.ncbi.nlm.nih.gov/pubmed/26883910
http://dx.doi.org/10.1186/s12896-016-0250-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755021/
https://www.ncbi.nlm.nih.gov/pubmed/26883910
http://dx.doi.org/10.1186/s12896-016-0250-4

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