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Death receptor-based enrichment of Cas9-expressing cells

BACKGROUND: The CRISPR/Cas9 genome editing system has greatly facilitated and expanded our capacity to engineer mammalian genomes, including targeted gene knock-outs. However, the phenotyping of the knock-out effect requires a high DNA editing efficiency. RESULTS: Here, we report a user-friendly str...

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Detalles Bibliográficos
Autores principales:	Liesche, C., Venkatraman, L., Aschenbrenner, S., Grosse, S., Grimm, D., Eils, R., Beaudouin, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755021/ https://www.ncbi.nlm.nih.gov/pubmed/26883910 http://dx.doi.org/10.1186/s12896-016-0250-4

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