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Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant

BACKGROUND: Annexin A2 (ANXA2) is a pleiotropic, calcium-dependent, phospholipid-binding protein with a broad tissue distribution. It can be intracellular, membrane-bound, or secreted, and it exists as a monomer or heterotetramer. The secreted ANXA2 heterotetramer signals human and murine macrophage...

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Detalles Bibliográficos
Autores principales: Andersen, Brian M., Xia, Junzhe, Epstein, Alan L., Ohlfest, John R., Chen, Wei, Blazar, Bruce R., Pennell, Christopher A., Olin, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755027/
https://www.ncbi.nlm.nih.gov/pubmed/26885373
http://dx.doi.org/10.1186/s40425-016-0112-6