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Switching STudy of Kidney TRansplant PAtients with Tremor to LCP‐TacrO (STRATO): an open‐label, multicenter, prospective phase 3b study

Tremor is a common side effect of tacrolimus correlated with peak‐dose drug concentration. LCPT, a novel, once‐daily, extended‐release formulation of tacrolimus, has a reduced C (max) with comparable AUC exposure, requiring a ~30% dose reduction vs. immediate‐release tacrolimus. In this phase 3b stu...

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Detalles Bibliográficos
Autores principales: Langone, Anthony, Steinberg, Steven M., Gedaly, Roberto, Chan, Laurence K., Shah, Tariq, Sethi, Kapil D., Nigro, Vincenza, Morgan, John C., Formica, Richard N., Barr, Yousri M., Brennan, Daniel C., El‐Amm, Jose‐Marie Albert, Kozlowski, Tomasz, Matas, Arthur Jeremy, West‐Thielke, Patricia M., Kistler, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755036/
https://www.ncbi.nlm.nih.gov/pubmed/26113208
http://dx.doi.org/10.1111/ctr.12581