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Switching STudy of Kidney TRansplant PAtients with Tremor to LCP‐TacrO (STRATO): an open‐label, multicenter, prospective phase 3b study
Tremor is a common side effect of tacrolimus correlated with peak‐dose drug concentration. LCPT, a novel, once‐daily, extended‐release formulation of tacrolimus, has a reduced C (max) with comparable AUC exposure, requiring a ~30% dose reduction vs. immediate‐release tacrolimus. In this phase 3b stu...
Autores principales: | Langone, Anthony, Steinberg, Steven M., Gedaly, Roberto, Chan, Laurence K., Shah, Tariq, Sethi, Kapil D., Nigro, Vincenza, Morgan, John C., Formica, Richard N., Barr, Yousri M., Brennan, Daniel C., El‐Amm, Jose‐Marie Albert, Kozlowski, Tomasz, Matas, Arthur Jeremy, West‐Thielke, Patricia M., Kistler, Kristin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755036/ https://www.ncbi.nlm.nih.gov/pubmed/26113208 http://dx.doi.org/10.1111/ctr.12581 |
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