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The rarity of ALDH (+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients

To understand the precise disease driving mechanisms in acute myeloid leukemia (AML), comparison of patient matched hematopoietic stem cells (HSC) and leukemia stem cells (LSC) is essential. In this analysis, we have examined the value of aldehyde dehydrogenase (ALDH) activity in combination with CD...

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Detalles Bibliográficos
Autores principales: Hoang, Van T., Buss, Eike C., Wang, Wenwen, Hoffmann, Isabel, Raffel, Simon, Zepeda‐Moreno, Abraham, Baran, Natalia, Wuchter, Patrick, Eckstein, Volker, Trumpp, Andreas, Jauch, Anna, Ho, Anthony D., Lutz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755039/
https://www.ncbi.nlm.nih.gov/pubmed/25545165
http://dx.doi.org/10.1002/ijc.29410