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The rarity of ALDH (+) cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients
To understand the precise disease driving mechanisms in acute myeloid leukemia (AML), comparison of patient matched hematopoietic stem cells (HSC) and leukemia stem cells (LSC) is essential. In this analysis, we have examined the value of aldehyde dehydrogenase (ALDH) activity in combination with CD...
Autores principales: | Hoang, Van T., Buss, Eike C., Wang, Wenwen, Hoffmann, Isabel, Raffel, Simon, Zepeda‐Moreno, Abraham, Baran, Natalia, Wuchter, Patrick, Eckstein, Volker, Trumpp, Andreas, Jauch, Anna, Ho, Anthony D., Lutz, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755039/ https://www.ncbi.nlm.nih.gov/pubmed/25545165 http://dx.doi.org/10.1002/ijc.29410 |
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