Bax assembles into large ring‐like structures remodeling the mitochondrial outer membrane in apoptosis

The Bcl‐2 family proteins Bax and Bak are essential for the execution of many apoptotic programs. During apoptosis, Bax translocates to the mitochondria and mediates the permeabilization of the outer membrane, thereby facilitating the release of pro‐apoptotic proteins. Yet the mechanistic details of...

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Detalles Bibliográficos
Autores principales: Große, Lena, Wurm, Christian A, Brüser, Christian, Neumann, Daniel, Jans, Daniel C, Jakobs, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755111/
https://www.ncbi.nlm.nih.gov/pubmed/26783364
http://dx.doi.org/10.15252/embj.201592789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755111/
https://www.ncbi.nlm.nih.gov/pubmed/26783364
http://dx.doi.org/10.15252/embj.201592789

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