Mangrove dolabrane‐type of diterpenes tagalsins suppresses tumor growth via ROS‐mediated apoptosis and ATM/ATR–Chk1/Chk2‐regulated cell cycle arrest

Natural compounds are an important source for drug development. With an increasing cancer rate worldwide there is an urgent quest for new anti‐cancer drugs. In this study, we show that a group of dolabrane‐type of diterpenes, collectively named tagalsins, isolated from the Chinese mangrove genus Cer...

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Detalles Bibliográficos
Autores principales: Neumann, Jennifer, Yang, Yi, Köhler, Rebecca, Giaisi, Marco, Witzens‐Harig, Mathias, Liu, Dong, Krammer, Peter H., Lin, Wenhan, Li‐Weber, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Cancer Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755134/
https://www.ncbi.nlm.nih.gov/pubmed/26061604
http://dx.doi.org/10.1002/ijc.29629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755134/
https://www.ncbi.nlm.nih.gov/pubmed/26061604
http://dx.doi.org/10.1002/ijc.29629

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