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Alterations of the spindle checkpoint pathway in clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas

CpG‐island methylator phenotype (CIMP)‐positive clear cell renal cell carcinomas (RCCs) are characterized by accumulation of DNA hypermethylation of CpG islands, clinicopathological aggressiveness and poor patient outcome. The aim of this study was to clarify the molecular pathways participating in...

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Detalles Bibliográficos
Autores principales: Arai, Eri, Gotoh, Masahiro, Tian, Ying, Sakamoto, Hiromi, Ono, Masaya, Matsuda, Akio, Takahashi, Yoriko, Miyata, Sayaka, Totsuka, Hirohiko, Chiku, Suenori, Komiyama, Motokiyo, Fujimoto, Hiroyuki, Matsumoto, Kenji, Yamada, Tesshi, Yoshida, Teruhiko, Kanai, Yae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755138/
https://www.ncbi.nlm.nih.gov/pubmed/26061684
http://dx.doi.org/10.1002/ijc.29630