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Regulation of germinal center B‐cell differentiation
Germinal centers (GC) are the main sites where antigen‐activated B‐cell clones expand and undergo immunoglobulin gene hypermutation and selection. Iterations of this process will lead to affinity maturation, replicating Darwinian evolution on the cellular level. GC B‐cell selection can lead to four...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755139/ https://www.ncbi.nlm.nih.gov/pubmed/26864101 http://dx.doi.org/10.1111/imr.12396 |