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Regulation of germinal center B‐cell differentiation

Germinal centers (GC) are the main sites where antigen‐activated B‐cell clones expand and undergo immunoglobulin gene hypermutation and selection. Iterations of this process will lead to affinity maturation, replicating Darwinian evolution on the cellular level. GC B‐cell selection can lead to four...

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Detalles Bibliográficos
Autores principales:	Zhang, Yang, Garcia‐Ibanez, Laura, Toellner, Kai‐Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Invited Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755139/ https://www.ncbi.nlm.nih.gov/pubmed/26864101 http://dx.doi.org/10.1111/imr.12396

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