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Refoldable Foldamers: Global Conformational Switching by Deletion or Insertion of a Single Hydrogen Bond
Small changes in the structure of a foldamer may lead to gross changes in conformational preference. We show that the simple insertion or deletion of a single hydrogen bond by changes in pH or by photochemical deprotection is sufficient to refold a helical oligomer, interconverting M and P screw‐sen...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755161/ https://www.ncbi.nlm.nih.gov/pubmed/26762559 http://dx.doi.org/10.1002/anie.201510605 |