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Mouse models of colorectal cancer as preclinical models

In this review, we discuss the application of mouse models to the identification and pre‐clinical validation of novel therapeutic targets in colorectal cancer, and to the search for early disease biomarkers. Large‐scale genomic, transcriptomic and epigenomic profiling of colorectal carcinomas has le...

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Detalles Bibliográficos
Autores principales: McIntyre, Rebecca E., Buczacki, Simon J.A., Arends, Mark J., Adams, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755199/
https://www.ncbi.nlm.nih.gov/pubmed/26115037
http://dx.doi.org/10.1002/bies.201500032