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Enantioselective Synthesis of 3,5,6‐Substituted Dihydropyranones and Dihydropyridinones using Isothiourea‐Mediated Catalysis

The scope of dihydropyranone and dihydropyridinone products accessible by isothiourea‐catalyzed processes has been expanded and explored through the use of 2‐N‐tosyliminoacrylates and 2‐aroylacrylates in a Michael addition‐lactonization/lactamization cascade reaction. Notably, to ensure reproducibil...

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Detalles Bibliográficos
Autores principales: Stark, Daniel G., Morrill, Louis C., Cordes, David B., Slawin, Alexandra M. Z., O'Riordan, Timothy J. C., Smith, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755233/
https://www.ncbi.nlm.nih.gov/pubmed/26471245
http://dx.doi.org/10.1002/asia.201500907