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Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis

Several human diseases, including Huntington's disease (HD), are associated with the expression of mutated, misfolded, and aggregation-prone amyloid proteins. Cardiac disease is the second leading cause of death in HD, which has been mainly studied as a neurodegenerative disease that is caused...

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Detalles Bibliográficos
Autores principales: Trujillo, Adriana S, Ramos, Raul, Bodmer, Rolf, Bernstein, Sanford I, Ocorr, Karen, Melkani, Girish C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755237/
https://www.ncbi.nlm.nih.gov/pubmed/26942103
http://dx.doi.org/10.4161/2167549X.2014.968003