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Impaired striatal function in Huntington's disease is due to aberrant p75NTR signaling
Huntington's disease (HD) is a rare genetic neurodegenerative disorder for which there is currently no cure. Early hyperkinetic motor symptoms are consistent with reduced activity of indirect pathway striatal projection neurons (iSPNs) responsible for suppression of unwanted actions. Our recent...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755240/ https://www.ncbi.nlm.nih.gov/pubmed/26942104 http://dx.doi.org/10.4161/2167549X.2014.968482 |