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The cGAS-STING Defense Pathway and Its Counteraction by Viruses
Upon virus infection, host cells mount a concerted innate immune response involving type I interferon and pro-inflammatory cytokines to enable elimination of the pathogen. Recently, cGAS and STING have been identified as intracellular sensors that activate the interferon pathway in response to virus...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Inc.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755325/ https://www.ncbi.nlm.nih.gov/pubmed/26867174 http://dx.doi.org/10.1016/j.chom.2016.01.010 |