Structure and function based design of Plasmodium-selective proteasome inhibitors

The proteasome is a multi-component protease complex responsible for regulating key processes such as the cell cycle and antigen presentation(1). Compounds that target the proteasome are potentially valuable tools for the treatment of pathogens that depend on proteasome function for survival and rep...

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Detalles Bibliográficos
Autores principales: Li, Hao, O'Donoghue, Anthony J., van der Linden, Wouter A., Xie, Stanley C., Yoo, Euna, Foe, Ian T., Tilley, Leann, Craik, Charles S., da Fonseca, Paula C. A., Bogyo, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755332/
https://www.ncbi.nlm.nih.gov/pubmed/26863983
http://dx.doi.org/10.1038/nature16936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755332/
https://www.ncbi.nlm.nih.gov/pubmed/26863983
http://dx.doi.org/10.1038/nature16936

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