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The business of deubiquitination – location, location, location

A majority of proteins in the cell can be modified by ubiquitination, thereby altering their function or stability. This ubiquitination is controlled by both ubiquitinating and deubiquitinating enzymes (DUBs). The number of ubiquitin ligases exceeds that of DUBs by about eightfold, indicating that D...

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Detalles Bibliográficos
Autores principales: Coyne, Erin S., Wing, Simon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755399/
https://www.ncbi.nlm.nih.gov/pubmed/26918171
http://dx.doi.org/10.12688/f1000research.7220.1