The Inhibitory Effect of Natural Products on Protein Fibrillation May Be Caused by Degradation Products – A Study Using Aloin and Insulin

Protein fibrillation is the pathological hallmark of several neurodegenerative diseases and also complicates the manufacturing and use of protein drugs. As a case study, the inhibitory activity of the natural compound aloin against insulin fibrillation was investigated. Based on Thioflavin T assays,...

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Detalles Bibliográficos
Autores principales: Lobbens, Eva S., Foderà, Vito, Nyberg, Nils T., Andersen, Kirsten, Jäger, Anna K., Jorgensen, Lene, van de Weert, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755604/
https://www.ncbi.nlm.nih.gov/pubmed/26882071
http://dx.doi.org/10.1371/journal.pone.0149148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755604/
https://www.ncbi.nlm.nih.gov/pubmed/26882071
http://dx.doi.org/10.1371/journal.pone.0149148

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