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Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes

The quality of mammalian oocytes declines with age, which negatively affects fertilization and developmental potential. The aging process often accompanies damages to macromolecules such as proteins, DNA, and lipids. To investigate if aged oocytes display an altered lipidome compared to young oocyte...

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Detalles Bibliográficos
Autores principales: Mok, Hyuck Jun, Shin, Hyejin, Lee, Jae Won, Lee, Geun-Kyung, Suh, Chang Suk, Kim, Kwang Pyo, Lim, Hyunjung Jade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755615/
https://www.ncbi.nlm.nih.gov/pubmed/26881843
http://dx.doi.org/10.1371/journal.pone.0148577